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Targeting the synaptic plasticity to manage chronic pain
时间:2018-12-21 08:40:13 阅读量:
报告题目:Targeting the synaptic plasticity to manage chronic pain
报 告 人:李相尧教授  浙江大学医学院
报告时间:2018年12月21日,下午16:00-17:00
报告地点:生科院一楼南厅
报告人简介:

  浙江大学医学院“百人计划”研究员,西安交通大学生命科学学院兼职教授,国家重点基础研究发展(973计划)-青年科学家专题首席科学家,浙江省特聘教授,浙江省生理科学会秘书长,浙江大学基础医学院生理学系副主任。主要研究方向为慢性痛及自闭症的神经机制。在国内、外学术期刊上发表论文30篇。研究论文发表在Science,Nature, The journal of Neuroscience等国际期刊上。本科和研究生均毕业于华东师范大学,2007年到加拿大多伦多大学进行博士后研究,2012年回国到西安交通大学,2014年7月到浙江大学医学院。
Selected Feature Articles:
(1) Li XY, Wang N, Wang YJ, Zuo ZX, Koga K, Luo F, Zhuo M*. Long-term temporal imprecision of information coding in the anterior cingulate cortex of mice with peripheral inflammation or nerve injury. J. Neurosci., 2014, 4(32):10675–10687.
(2) Wang YJ, Zuo ZX, Wu C, Liu L, Feng ZH, Li XY*. Cingulate Alpha-2A Adrenoceptors Mediate the Effects of Clonidine on Spontaneous Pain Induced by Peripheral Nerve Injury. Frontiers in Molecular Neuroscience, 2017, Sep 12;10:289.
(3) Zuo ZX+, Wang YJ+, Liu L, Wang Y, Mei SH, Feng ZH, Wang M*, Li XY*. Huperzine A alleviates mechanical allodynia but not spontaneous pain via muscarinic acetylcholine receptors in mice. Neural Plasticity, 2015:453170.
(4) Wang YJ, Zuo ZX, Zhang M, Feng ZH, Yan M*, Li XY*,The analgesic effects of (5R,6R)6-(3-propylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1] octane (PTAC) on a mouse model of neuropathic pain. Anesthesia & Analgesia.2017, 24(4):1330-1338.
(5) Tian Y, Yang C, Cui Y, Su F, Wang Y, Wang Y, Yuan P, Shang S, Li H, Zhao J, Zhu D, Tang S, Cao P, Liu Y, Wang X, Wang L, Zeng W, Jiang H, Zhao F, Luo M, Xiong W, Qiu Z*, Li XY*, Zhang C*. An Excitatory Neural Assembly Encodes Short-Term Memory in the Prefrontal Cortex, Cell Rep. 2018 Feb 13;22(7):1734-1744.
(6) Li XY+, Ko HG+, Chen T+, Descalzi G, Koga K, Wang H, Kim SS, Shang Y, Kwak C, Park SW, Shim J, Lee K, Collingridge GL, Kaang BK, Zhuo M*. Alleviating neuropathic pain hypersensitivity by inhibiting PKMzeta in the anterior cingulate cortex. Science. 2010; 330(6009):1400-4. (+Equal contributor, Science signaling Editor’s choice, Nature highlighted, F1000 highlighted).